Skin Care that tames hormones impacts. But there are also many new topical treatments to try. Some contain substances that simulate what real hormones do in your skin, says Mamina Turegano, M.D., a dermatologist in Louisiana. “The benefit of using those is they get to the root cause of the issue,” she says. Another approach: Emepelle Eye Cream has a patented ingredient that helps restore the function of estrogen-deficient skin.