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Emepelle Serum

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Emepelle Serum is a lightweight, oil-free daily serum that helps to reinvigorate skin’s natural source of radiance for more healthy, youthful-looking skin. This silky smooth serum features MEP Technology™ to help restore the natural function of Estrogen Deficient Skin non-hormonally for improved firmness, hydration and luminosity1. The result is more hydrated and luminous skin. Emepelle Serum is a breakthrough serum designed for women in menopause and perimenopause to directly combat signs of estrogen loss and skin aging.

  • Targets the root cause of Estrogen Deficient Skin non-hormonally with exclusive MEP Technology with clinically proven results
  • Also contains antioxidants, niacinamide, peptides and hyaluronic acid
  • Fast absorbing, suitable for layering with other products and under makeup
  • Gluten-free, paraben-free

Size: 1.2 fl oz

SKU: SERUM35EME Product Types: , , Skincare Concerns: ,

Related Skincare Concerns

  • Estrogen Deficient Skin
  • Dry skin
  • Dull skin
  • Sagging skin

Clinical Results

Emepelle is clinically proven2 to help address accelerated collagen loss and skin aging due to Estrogen Deficient Skin. In a clinical study using Emepelle Serum and Emepelle Night Cream for 8 weeks:

  • 100% of study participants showed improvement in skin hydration
  • 93% of study participants agreed that Emepelle improved the appearance of their skin
  • 64% of study participants saw a reduction in wrinkles

Key Ingredients

MEP Technology® – Helps address the root cause of Estrogen Deficient Skin, non-hormonally to revitalize skin’s natural source of radiance
Vitamins C & E and Ferulic Acid – Powerful blend of antioxidants for free radical defense
Niacinamide – Helps brighten and even skin tone, improve texture, smooth the appearance of fine lines and wrinkles and provide additional antioxidant protection
Peptides – Helps combat oxidative stress and improve the appearance of fine lines, wrinkles and skin laxity
Hyaluronic Acid – Helps improve hydration and supports the skin’s moisture barrier

Show Full Ingredient List

How to Use

Apply one pump evenly to cleansed, dry skin. Use once or twice daily. For morning use, follow with sunscreen. For optimal results, use Emepelle Serum in the morning and Emepelle Night Cream in the evening.



8 weeks later



  1. Michelle

    This serum is so lightweight and instantly absorbs into my skin. I love that it hydrates, protects, addresses loss of collagen and enhances skins radiance. My skin felt soft as silk with a glowing, youthful complexion. What more can you ask for in a serum? I received this in exchange for my honest opinion.

  2. Kelly Heflin

    I’m kind of a product junkie. I absolutely love trying new skin care products, and I’ve tried just about every brand at some point, ditching some and sticking with few. Biopelle is one of the few that I have stuck with. I was a little unsure what the Emepelle serum really was, but was instantly intrigued. Morning and night, I put one full pump on my face and neck, smoothing the light, fresh smelling serum all over. It feels refreshing and soothing and on my skin right away. I can’t say that I noticed my skin looking firming the first night, but I thought I looked more awake and refreshed the next day. After about a week of continual use, I started noticing fine lines less pronounced, and my tired skin looked more rejuvenated. My skin feels more plump and filled in, which is really saying a lot– MANY products promise this, but don’t deliver. I’ve been using this product consistently for over a month now. I never use a product that consistently (I get antsy and want to try new things!), so it’s saying a lot that I notice that much of a difference to keep using it every day and night. While pricey, I still have a majority of the bottle left after using so often, so that’s promising that I’m getting my money’s worth. And for results like this, I don’t mind a pricier product– I’d rather get something that works than a drawer full of bottles that are untouched. Try Biopelle Emepelle, you won’t regret it!!

  3. Tynish Flowers

    I am so thankful that I was sent this serum to review because I absolutely love it. I love that it is lightweight and only takes one pump. I use it right after cleansing my face. This serum has definitely brought a glow back to my skin. I have always dealt with dry skin and after 4 weeks of using this serum my skin’s hydration has drastically improved. I use this serum in the morning and the Night Cream before bed and my skin looks amazing.

MEP Technology

For Estrogen Deficient Skin

Breakthrough MEP Technology does what other anti-aging products are simply not able to do. MEP helps address a root cause of accelerated skin aging in Estrogen Deficient Skin to restore its natural function, non-hormonally.

MEP is clinically proven to safely and effectively help improve dryness, dullness, laxity, atrophy and the appearance of fine lines for more healthy, youthful-looking skin.

Learn more about MEP Technology

MEP Technology

Learn more about MEP Technology




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(vs 16% improvement with placebo)


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(vs 8% improvement with placebo)


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(vs 6% improvement with placebo)

Frequently Asked Questions

Estrogen Deficient Skin results in noticeable dryness, dullness, sagging, thinning, fine lines and/or wrinkling of facial skin. It typically becomes apparent in peri-menopause and menopause, when estrogen levels in the body begin to decline. If you feel like your moisturizer is no longer working or like your skin has lost its luminosity or youthful “glow”,  you may be experiencing Estrogen Deficient Skin.

Emepelle Serum helps improve skin’s health and appearance, including hydration and the appearance of  firmness and luminosity.  In a clinical study, after 14 weeks of application of MEP Technology, 54% of users saw more hydrated skin, 39% saw an increase in luminosity and 19% saw an improvement in laxity.

In clinical studies, Emepelle  made a marked improvement in users’ skin after only eight weeks of use, though the timeframe of results may vary.

No. Emepelle serum is a non-hormonal skincare solution aimed at improving the effects of estrogen loss and skin aging. It does not contain estrogen and has benefits exclusively to the skin. 

It is normal to experience mild tingling unaccompanied by irritation with the use of Emepelle Serum. If irritation or redness develops, discontinue use, at least temporarily.<

Emepelle is non-hormonal. MEP Technology has been clinically proven to be safe though it has not been tested on individuals with specific medical conditions. Please consult your doctor with any questions.

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