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Emepelle Serum

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Emepelle Serum is a lightweight, oil-free daily serum that helps to reinvigorate skin’s natural source of radiance for more healthy, youthful-looking skin. This silky smooth serum features MEP Technology™ to help restore the natural function of Estrogen Deficient Skin non-hormonally for improved firmness, hydration and luminosity1. The result is more hydrated and luminous skin. Emepelle Serum is a breakthrough serum designed for women in menopause and perimenopause to directly combat signs of estrogen loss and skin aging.

  • Targets the root cause of Estrogen Deficient Skin non-hormonally with exclusive MEP Technology with clinically proven results
  • Also contains antioxidants, niacinamide, peptides and hyaluronic acid
  • Fast absorbing, suitable for layering with other products and under makeup
  • Gluten-free, paraben-free

Size: 1.2 fl oz

SKU: SERUM35EME Product Types: , , Skincare Concerns: ,

Related Skincare Concerns

  • Estrogen Deficient Skin
  • Dry skin
  • Dull skin
  • Sagging skin

Clinical Results

Emepelle is clinically proven2 to help address accelerated collagen loss and skin aging due to Estrogen Deficient Skin. In a clinical study using Emepelle Serum and Emepelle Night Cream for 8 weeks:

  • 100% of study participants showed improvement in skin hydration
  • 93% of study participants agreed that Emepelle improved the appearance of their skin
  • 64% of study participants saw a reduction in wrinkles

Key Ingredients

MEP Technology® – Helps address the root cause of Estrogen Deficient Skin, non-hormonally to revitalize skin’s natural source of radiance
Vitamins C & E and Ferulic Acid – Powerful blend of antioxidants for free radical defense
Niacinamide – Helps brighten and even skin tone, improve texture, smooth the appearance of fine lines and wrinkles and provide additional antioxidant protection
Peptides – Helps combat oxidative stress and improve the appearance of fine lines, wrinkles and skin laxity
Hyaluronic Acid – Helps improve hydration and supports the skin’s moisture barrier

Show Full Ingredient List

How to Use

Apply one pump evenly to cleansed, dry skin. Use once or twice daily. For morning use, follow with sunscreen. For optimal results, use Emepelle Serum in the morning and Emepelle Night Cream in the evening.



8 weeks later



  1. Deborah Dennert (verified owner)

    I, too, am a skincare junkie. I have loved using this serum and I use the night cream every other night (because of cost). I ordered a second bottle of the serum during a sale. I have had people ask me what I’m doing to my skin and why I don’t look my age. I will be 70 in July and have been complimented several times by women friends. One of my Facebook friends messaged me to ask who my Dermatologist was and I told her ME!

  2. C

    I have been using for 8 weeks. In the first three weeks or so compliments from family and questions about what am I doing as my skin “ looks good”. Pores are refined / skin is soother / increased hydration and glow . As time went on the pores became more refined and my cheeks and forehead smooth. Hoping for results around my mouth area with on going use. I also use the night cream. A little goes a long way. I am still on my first bottles I am in Canada so am hoping that soon it will be available here. It is expensive but again a little goes a long way and the results are impressive

  3. Jennifer Soltys

    The easy-to-use pump on the bottle makes this serum so easy to apply. The serum is light and glides on very nicely. I love that it’s not heavily-perfumed. It does have a light scent that I do not love, but it fades quickly and doesn’t bother me too much. I realized after the first use that a little goes a long way. I thought I needed 2 pumps, but 1 is definitely enough. The serum absorbs quickly, and I am able to apply makeup shortly after (not that I do that much these days, but it’s good to know!) My skin feels noticeably more hydrated, smoother, and overall brighter after using this serum for about a month. It will definitely stay in my daily routine! Product received in exchange for my honest review.

MEP Technology

For Estrogen Deficient Skin

Breakthrough MEP Technology does what other anti-aging products are simply not able to do. MEP helps address a root cause of accelerated skin aging in Estrogen Deficient Skin to restore its natural function, non-hormonally.

MEP is clinically proven to safely and effectively help improve dryness, dullness, laxity, atrophy and the appearance of fine lines for more healthy, youthful-looking skin.

Learn more about MEP Technology

MEP Technology

Learn more about MEP Technology




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(vs 16% improvement with placebo)


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(vs 8% improvement with placebo)


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(vs 6% improvement with placebo)

Frequently Asked Questions

Estrogen Deficient Skin results in noticeable dryness, dullness, sagging, thinning, fine lines and/or wrinkling of facial skin. It typically becomes apparent in peri-menopause and menopause, when estrogen levels in the body begin to decline. If you feel like your moisturizer is no longer working or like your skin has lost its luminosity or youthful “glow”,  you may be experiencing Estrogen Deficient Skin.

Emepelle Serum helps improve skin’s health and appearance, including hydration and the appearance of  firmness and luminosity.  In a clinical study, after 14 weeks of application of MEP Technology, 54% of users saw more hydrated skin, 39% saw an increase in luminosity and 19% saw an improvement in laxity.

In clinical studies, Emepelle  made a marked improvement in users’ skin after only eight weeks of use, though the timeframe of results may vary.

No. Emepelle serum is a non-hormonal skincare solution aimed at improving the effects of estrogen loss and skin aging. It does not contain estrogen and has benefits exclusively to the skin. 

It is normal to experience mild tingling unaccompanied by irritation with the use of Emepelle Serum. If irritation or redness develops, discontinue use, at least temporarily.<

Emepelle is non-hormonal. MEP Technology has been clinically proven to be safe though it has not been tested on individuals with specific medical conditions. Please consult your doctor with any questions.

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